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2010

• Docampo, R., Ulrich, P., and Moreno, S.N.J. (2010) Evolution of acidocalcisomes and their role in polyphosphate storage and osmoregulation in eukaryotic microbes. Phil. Trans. R. Soc. B, in press.
• Ulrich, P., Cintrón-Moret, R., and Docampo, R. (2010) Calcium homeostasis and acidocalcisomes in Trypanosoma cruzi. Microbiol. Monograps. Springer-Verlag Verlin Heidelberg, in press.
• Lander, N., Bernal, C., Diez, N., Añez, N., Docampo, R., and Ramirez, J.J. (2010) Localization and developmental regulation of a dispersed gene family-1 (DGF-1) protein in Trypanosoma cruzi. Inf. Immun., in press. Published ahead of print on 19 October 2009.

2009

• Patel, S., and Docampo, R. (2009) In with the TRP channels: intracellular functions for TRPM1 and TRPM2. Sci Signal. 2 (95) pe69.
• Donald, B., Cannon, G., Dahl, C., Docampo, R., Fuerst, J., Heinhorst, S., Maupin-Furlow, J., Pfeifer, F., Preiss, J., Schüler, D., Steinbüchel, A., and Shively, J. (2009) Intracellular structures of Prokaryotes: Inclusions, compartments and assemblages. In: The Encyclopedia of Microbiology, 3rd Edition. Schaechter, M., Ed. Elsevier, p. 404-424.
• Motta, L.S., Ramos, I.B., Gomes, F.M., de Souza, W., Champagne, D.E, Santiago, M.F., Docampo, R., Miranda, K., and Machado, E.A. (2009) Proton-pyrophosphatase and polyphosphate in acidocalcisome-like vesicles from oocytes and eggs of Periplaneta Americana. Insect Biochem. Mol. Biol. 39, 198-206.
• Mezencev, R., Galizzi, M., Kutschy, P., and Docampo, R. (2009) Trypanosoma cruzi: antiproliferative effect of indole phytoalexins on intracellular amastigotes in vitro. Exp. Parasitol. 122, 66-69.
• Moreno, S.N.J., and Docampo, R. (2009) The role of acidocalcisomes in parasitic protists. J. Eukaryot. Microbiol. 56, 208-213.

2008

• Salto, L., Kuhlenschmidt, T, Kuhlenschmidt, M, and Docampo, R. (2008) Phospholipid and glycolipid composition of acidocalcisomes of Trypanosoma cruzi. Mol. Biochem. Parasitol., 158:120-130.
• Rohloff, P. and Docampo, R. (2008) A contractile vacuole complex is involved in osmoregulation in Trypanosoma cruzi. Exp. Parasitol. 118, 17-24.
• Moreno S.N.J., Li Z.H. (2008). Targeting the isoprenoid pathway of Toxoplasma gondii. Expert Opin Ther Targets. 2008 Mar;12(3):253-63.
• Miranda, K. de Souza, W. Plattner, H. Hentschel, J. Kawazoe, U. and Moreno, SNJ. (2008) Acidocalcisomes in Apicomplexan parasites . Exp. Parasitol.,118:2-9.
• Docampo, R. (2008) Special section on novel organelles in parasitic protozoa. Exp. Parasitol. 118, 1.
• Docampo, R., and Moreno, S.N. (2008) The acidocalcisome as a target for chemotherapeutic agents in protozoan parasites. Curr. Pharm. Design,14, 882-888.
• Szajnman, S.H., García Liñares, G.G., Li, Z-H., Jang, C., Galizzi, M., Bontempi, E., Ferella, M., Moreno, S.N.J., Docampo, R., and Rodriguez, J.B. (2008) Synthesis and biological evaluation of 2-alkylaminoethyl-1,1-bisphosphonic acids against Trypanosoma cruzi and Toxoplasma gondii targeting farnesyl diphosphate synthase. Bioorg. Med. Chem.,16, 3283-3290.
• Ferella, M., Nilsson, D., Darban, J., Rodrigues, C.O., Bontempi, E.J., Docampo, R., Andersson, B. (2008) Proteomics in Trypanosoma cruzi - Localization of novel proteins to various organelles. Proteomics, 8, 2735-2749.
• Ferella, M., Li, Z.H., Andersson, B., and Docampo, R. (2008) Farnesyl diphosphate synthases localizes to the cytosol of Trypanosoma cruzi and T. brucei. Exp. Parasitol., 119, 308-312.
• Schoijet, A. Miranda, K., Girard-Dias, W., de Souza, W., Flawia, M.M., Torres, H.N., Docampo, R., and Alonso, G. (2008) A Trypanosoma cruzi phosphatidylinositol-3-kinase (TcVps34) is involved in osmoregulation and receptor-mediated endocytosis. J. Biol. Chem. 283, 31541-31550.
• Nagamune, K., Moreno, S.N., Chini, E.N., Sibley, L.D. (2008) Calcium regulation and signaling in apicomplexan parasites. Subcell Biochem. 47, 70-81.

2007

• Nagamune K, Beatty WL, Moreno SN, Sibley, LD. Artemisinin induces calcium-dependent secretion in Toxoplasma gondii (2007) Antimicrob. Agents Chemother. 51(11):3816-23.
• Ling Y, Li ZH, Miranda K, Oldfield E, Moreno SN. The farnesyl diphosphate/geranylgeranyl diphosphate synthase of Toxoplasma gondii is a bifunctional enzyme and the molecular target of bisphosphonates (2007) J. Biol. Chem. 282(42):30804-16.
• Fang, J., Rohloff, P., Miranda, K., and Docampo, R. (2007) Ablation of a small transmembrane protein of Trypanosoma brucei (TbVTC1) involved in the synthesis of polyphosphate alters acidocalcisome biogenesis and function, and leads to a cytokinesis defect. Biochem. J. 407, 161-170.
• Fang, J., Ruiz, F.A., Docampo, M., Luo, S., Rodrigues, J.C., Motta, L.S., Rohloff, P., and Docampo, R. (2007) Overexpression of a Zn2+-sensitive soluble exopolyphosphatase from Trypanosoma cruzi depletes polyphosphate and affects osmoregulation. J. Biol. Chem. 282, 32501-32510.
• Linares GG, Gismondi S, Codesido NO, Moreno SN, Docampo R, Rodriguez JB. Fluorine-containing aryloxyethyl thiocyanate derivatives are potent inhibitors of Trypanosoma cruzi and Toxoplasma gondii proliferation. Bioorg Med Chem Lett. 2007 Sep 15;17(18):5068-5071.
• Moreno SN. Drugs Against Protozoan Parasites - a Keystone Symposium. IDrugs. 2007 10(4):240-2.
• Moreno, S.N.J., Miranda, K., Fang, J., Rohloff, P. and de Souza. W. (2007) Calcium storage and homeostasis in Toxoplasma gondii. In: “Toxoplasma gondii: The Model Apicomplexan---Perspective and Methods”. Editors: Louis M. Weiss and Kami Kim. Elsevier-Academic Press. Chapter 10.
• Nagamune, K., Moreno, S.N.J., Chini, E. N. and Sibley, L. D. (2007). Calcium regulation and signaling in apicomplexan parasites In: “Molecular Mechanisms of Parasite Invasion”. Editors: Barbara Burleigh and Dominique Soldati. In press.
• Moreno, S.N.J., Miranda, K. and De Souza, W. (2007). Calcium homeostasis and acidocalcisomes in Toxoplasma gondii. In:The biology of Toxoplasma gondii. Eds: James Ajioka and Dominique Soldati. Horizon Scientific press. Chapter 26. 

2006

• Fang J, Marchesini N, Moreno SN. (2006) A Toxoplasma gondii phosphoinositide phospholipase C (TgPI-PLC) with high affinity for phosphatidylinositol. Biochem J.394:417.
• Harper JM, Huynh MH, Coppens I, Parussini F, Moreno SN, Carruters VB. A Cleavable Propeptide Influences Toxoplasma Infection by Facilitating the Trafficking and Secretion of the TgMIC2-M2AP Invasion Complex. (2006) Mol. Biol. Cell. 17(10):4551-63.
• Ravaschino, E., Docampo, R., and Rodriguez, J.B. (2006) Design, synthesis, and biological evaluation of phosphinopeptides against Trypanosoma cruzi targeting trypanothione biosynthesis. J. Med. Chem. 49, 426-435.
• Gabelli, S. B., McLellan, J. S., Montalvetti, A., Oldfield, E., Docampo, R., and Amzel, L. M. (2006) Structure and mechanism of the farnesyl diphosphate synthase from Trypanosoma cruzi: implications for drug design. Proteins 62, 80-88.
• Smith, S.A., Mutch, N.J., Baskar, D., Rohloff, P., Docampo, R., and Morrissey, J.H. (2006) Polyphosphate modulates blood coagulation and fibrinolysis. Proc. Natl. Acad. Sci. U.S.A., 103, 903-908.
• Luo, S., Fang, J., and Docampo, R. (2006) Molecular characterization of Trypanosoma brucei P-type H+-ATPases. J. Biol. Chem. 281, 21963-21973.
  Rohloff, P., and Docampo, R. (2006) Ammonium production during hypo-osmotic stress leads to alkalinization of acidocalcisomes and cytosolic acidification in Trypanosoma cruzi. Mol. Biochem. Parasitol. 150, 249-255.
• Ferella, M., Montalvetti, A., Rohloff, P., Miranda, K., Fang, J., Reina, S., Kawamaki, M., Búa, J., Nilsson, D., Pravia, C., Katzin, A., Cassera, M.B., Aslund, L., Andersson, B., Docampo, R., and Bontempi, E.J. (2006) A solanesyl-diphosphate synthase localizes I glycosomes of Trypanosoma cruzi. J. Biol. Chem. 281, 39339-39348.
• Shively, J.M., Cannon, G.C., Heinhorst, S., Bryant, D.A., DasSarma, S., Bazylinski, D., Preiss, J., Steinbüchel, A., Docampo, R., and Dahl, C. (2006) Bacterial Inclusions. In: Encyclopedia of Life Sciences. John Wiley & Sons, pp 1-11.
• Docampo, R. (2006) Acidocalcisomes and polyphosphate granules. In: Microbiology Monographs. Springer-Verlag Berlin Heidelberg, pp. 53-70.

2005

• Luo, S., Ruiz, F.A., and Moreno, S.N.J. (2005) The acidocalcisome Ca2+-ATPase (TgA1) of Toxoplasma gondii is required for polyphosphate storage, intracellular calcium homeostasis and virulence. Mol. Microbiol. 55:1034-1045.
• Marshesini N, Vieira, M. Moreno, S.N.J., Docampo, R. A malaria parasite-encoded vacuolar H(+)-ATPase is targeted to the host erythrocyte (2005). J. Biol. Chem.  280: 36841-7.
• Miranda, K., Vercesi, A.E., Catisti, R., de Souza, W., Rodrigues, C.O., and Docampo, R. (2005) P-type proton ATPases are involved in intracellular calcium and proton uptake in the plant parasite Phytomonas francai. J. Eukar. Microbiol. 52, 55-60.
• Docampo, R., de Souza, W., Miranda, K., Rohloff, R., and Moreno, S.N.J. (2005) Acidocalcisomes –conserved from bacteria to man. Nat. Rev. Microbiol. 3:251-261.
• Okura M, Fang J, Salto ML, Singer RS, Docampo R, Moreno S.N.J. (2005) A lipid-modified phosphoinositide-specific phospholipase C (TcPI-PLC) is involved in differentiation of trypomastigotes to amastigotes of Trypanosoma cruzi. J. Biol. Chem. 280:16235-43.
• Ling, Y., Sahota, G., Odeh, S., Chan, J.M., Araujo, F., Moreno, S.N.J. and Oldfield, E. (2005) Bisphosphonate inhibitors of Toxoplasma gondii growth: in vitro, QSAR and in vivo investigations. J. Med. Chem. 48:3130-3140.
• Zhang, K., Hsu, F.-F., Scott, D. A., Docampo, R., Turk, J., and Beverley, S. M. (2005) Leishmania salvage and remodeling of host sphingolipids in amastigote survival and acidocalcisome biogenesis. Mol. Microbiol. 55, 1566-1578.
• Cuevas, I. C., Rohloff, P., Sanchez, D. O. and Docampo, R. (2005) Characterization of farnesylated protein tyrosine phosphatase TcPRL-1 from Trypanosoma cruzi. Euk. Cell 4, 1550-11561.
• Kotsikorou, E., Song, Y., Chan, J., Faelens, S., Tovian, Z., Broderick, E., Bakalara, N., Docampo, R., and Oldfield, E. (2005) Bisphosphonate inhibition of the exopolyphosphatase activity of the Trypanosoma brucei soluble pyrophosphatase. J. Med. Chem. 48, 6128-6139.
• Vieira, M., Rohloff, P., Luo, S., Cunha-e-Silva, N., de Souza, W., and Docampo, R. (2005) Role for a P-type H+-ATPase in the acidification of the endocytic pathway of Trypanosoma cruzi. Biochem. J. 392, 467-474.
• Szajnman, S. H., Ravaschino, E. L., Docampo, R., and Rodriguez, J. B. (2005) Synthesis and biological evaluation of 1-amino-1,1-bisphosphonates derived from fatty acids against Trypanosoma cruzi targeting farnesyl pyrophosphate synthase. Bioorg. Med. Chem. Lett. 15, 4685-4690.

2004

• Arrizabalaga, G., Ruiz, F., Moreno, S.N.J. and Boothroyd, J.A. (2004) Ionophore-resistant mutant of Toxoplasma gondii reveals involvement of a sodium/hydrogen exchanger in calcium regulation. J. Cell Biol. 165:653-662.
• Wetzel, D.M., Chen, L.A., Ruiz, F.A., Moreno, S.N.J., and Sibley, L.D. (2004) Calcium-mediated protein secretion potentiates motility by Toxoplasma gondii. J. Cell Sci. 117: 5739-5748.
• Uyemura, S.A., Luo, S., Vieira, M., Moreno, S.N.J. and Docampo, R. Oxidative phosphorylation and rotenone-insensitive malate- and NADH-quinone oxidoreductases in Plasmodium yoelii mitochondria in situ (2004) J. Biol. Chem.  279(1):385-93.
• Lemercier, G., Espiau, B., Ruiz, F.A., Vieira, M., Luo, S., Baltz, T., Docampo, R., a\nd Bakalara, N. (2004) A pyrophosphatase regulating polyphosphate metabolism in acidocalcisomes is essential for Trypanosoma brucei virulence in mice. J. Biol. Chem. 279, 3420-3425.
• Luo, S., Rohloff, P., Cox, J., Uyemura, S. A., and Docampo, R. (2004) Trypanosoma brucei plasma membrane-type Ca2+-ATPase 1 (TbPMC1) and 2 (TbPMC2) genes encode functional Ca2+-ATPases localized to the acidocalcisomes and plasma membrane, and essential for Ca2+ homeostasis and growth. J. Biol. Chem. 279, 14427-14439.
• Miranda, K., Docampo, R., Grillo, O., Franzen, A., Attias, M., Vercesi, A., Plattner, H., Hentschel, J., and de Souza, W. (2004) Dynamics of polymorphism of acidocalcisomes in Leishmania parasites. Histochem. Cell Biol. 121, 407-418
• Montalvetti, A., Rohloff, P., and Docampo, R. (2004) A functional aquaporin co-localizes with the vacuolar proton pyrophosphatase to acidocalcisomes and the contractile vacuole complex of Trypanosoma cruzi. J. Biol. Chem. 279, 38673-38682.
• Mao, J., Gao, Y.-G., Odeh, S., Robinson, H., Montalvetti, A., Docampo, R., and Oldfield, E. (2004) Crystallization and preliminary X-ray diffraction study of the farnesyl diphosphate synthase from Trypanosoma brucei. Acta Crystallographica Section D 60, 1863-1866.
• Ruiz, F. A., Lea, C. R., Oldfield, E., and Docampo, R. (2004) Human platelet dense granules contain polyphosphate and are similar to acidocalcisomes of bacteria and unicellular eukaryotes. J. Biol. Chem. 279, 44250-44257.
• Seufferheld, M., Lea, C., Vieira, M., Oldfield, E., and Docampo, R. (2004) The H+-pyrophosphatase of Rhodospirillum rubrum is predominantly located in polyphosphate-rich acidocalcisomes. J. Biol. Chem. 279, 51193-51202.
• Rohloff, P., Montalvetti, A., and Docampo, R. (2004) Acidocalcisomes and the contractile vacuole are involved in osmoregulation in Trypanosoma cruzi. J. Biol. Chem. 279, 52270-52281.
• Miranda, K., Docampo, R., Grillo, O., and de Souza, W. (2004) Acidocalcisomes of trypanosomatids have species-specific elemental composition. Protist 155, 395-405.
• Ruiz, F.A., Luo, S., Moreno, S.N.J., and Docampo, R. (2004) Polyphosphate content and fine structure of acidocalcisomes of Plasmodium falciparum. Microsc. Microanal.10(5);117(pt 24):5739-48.
• Miranda, K., Rodrigues, C.O., Hentchel, J., Vercesi, A., Plattner, H., de Souza, W., and Docampo, R. (2004) Acidocalcisomes of Phytomonas françai possess distinct morphological characteristics and contain iron. Micro. Microanal. 10, 647-655.
• Docampo, R. (2004) Introduction: A special issue on cellular biology of protozoan parasites. Microsc. Microanal. 10, 511-512.
• Docampo, R. (2004) Conference summary: New and re-emerging infectious diseases. Emerging Infect. Dis. 10, 1891.
• Docampo, R., and Moreno, S. N. J. (2004) Wide distribution and function of the H+-pyrophosphatase in prokaryotic and eukaryotic organelles. In; Recent Advances in Inorganic Pyrophosphate Research. Edited by S. A. White, University of Birmingham, pp. 81-85.

2003

• Salto, M. L., Bertello, L. E. Vieira, M.C.F., Docampo, R., Moreno, S.N.J., Lederkremer, R.M. (2003). Formation and remodeling of inositolphosphoceramide during the differentiation of trypomastigote into amastigote forms of Trypanosoma cruzi. Eukaryotic Cell 2, 756-768.
• Docampo, R., and Moreno, S.N.J. (2003) Current chemotherapy of human African trypanosomiasis. Parasitol. Res., 90 Supp 1:S10-3.
  Seufferheld, M., Vieira, M.C.F., Ruiz, F.A., Rodrigues, C.O., Moreno, S.N.J., and Docampo, R. (2003) Identification in bacteria of organelles similar to acidocalcisomes of unicellular eukaryotes. J. Biol. Chem. 278, 29971 – 29978
• Moreno, S.N.J., and Docampo, R. (2003) Calcium regulation in protozoan parasites. Curr. Opinion Microbiol. 6, 359-364.
• Moreno, S.N.J., and Docampo, R. (2003) Ca2+ signaling in the invasion of mammalian cells by Trypanosoma cruzi. In: "Molecular Mechanisms of Chagas' Disease Pathogenesis". Edited by J. M. Kelly, Eurekah,. Chapter 5, pp. 73-83.
• Rohloff, P., Rodrigues, C.O., and Docampo, R. (2003) Regulatory volume decrease in Trypanosoma cruzi involves amino acid efflux and changes in intracellular calcium. Mol. Biochem. Parasitol. 126, 219-230.
• Montalvetti, A., Fernandez, A., Sanders, J.M., Ghosh, S., Van Brussel, E., Oldfield, E., and Docampo, R. (2003) Farnesyl pyrophosphate synthase is an essential enzyme in Trypanosoma brucei. In vitro RNA interference and in vivo inhibition studies. J. Biol. Chem. 278, 1075-1083.
• Urbina, J.A., Concepcion, J.J., Montalvetti, A., Rodriguez, J.B., and Docampo, R. (2003) Mechanism of action of 4-phenoxyphenoxyethyl thiocyanate (WC-9) against Trypanosoma cruzi, the causative agent of Chagas' disease. Antimicrob. Agents Chemother. 47, 2047-2050.
• Conte, I., Labriola, C., Cazzulo, J.J., Docampo, R., and Parodi, A.J. (2003) The interplay between folding facilitating mechanisms in Trypanosoma cruzi endoplasmic reticulum. Mol. Biol. Cell 14, 3529-3540.
• Szajnman, S.H., Montalvetti, A., Wang, Y., Docampo, R., and Rodriguez, J.B. (2003) Bisphosphonates derived from fatty acids are potent inhibitors of Trypanosoma cruzi farnesyl pyrophosphate synthase. Bioorg. Med. Chem. Lett. 13, 3231-3235.
• Ravaschino, E.L., Docampo, R., and Rodriguez, J.B. (2003) Synthesis and biological evaluation of glutathione-like tripeptides against Trypanosoma cruzi. Arkivoc 10, 298-313.
• Garzoni, L.R., Caldera, A., Meirelles, M.N., de Castro, S.L., Docampo, R., Meints, G.A., Oldfield, E., Urbina, J.A. (2003) Selective in vitro effects of the farnesyl pyrophosphate synthase inhibitor risedronate on Trypanosoma cruzi. Int. J. Antimicrob. Agents 23, 273-285.
• Garzoni, L.R., Waghabi, M.C., Baptista, M.M., de Castro, S.L., Meirelles, M.N., Britto, C.C., Docampo, R., Oldfield, E., and Urbina, J.A. (2003) Antiparasitic activity of risedronate in a murine model of acute Chagas' disease. Int. J. Antimicrob. Agents 23, 286-290.
• Urbina, J.A., and Docampo, R. (2003) Specific chemotherapy of Chagas disease: controversies and advances. Trends Parasitol. 19, 495-501.
• Docampo, R. (2003) Chemotherapeutic Targets in Parasites. J. Eukar. Microbiol. 50, 144.
• Docampo, R. (2003) New and re-emerging Infectious diseases. Emerging Infect. Dis. 9, 1030-1033.

2002

• Salto, M.L., Furuya, T., Moreno, S.N.J., Docampo, R. and Lederkremer, R.M. (2002) The phosphatidylinositol-phospholipase C from Trypanosoma cruzi is active on inositolphosphoceramide. Mol. Biochem. Parasitol. 119, 131-133.
• Yardley, V., Khan, A.A., Martin, M.B., Slifer, T.R., Araujo, F.G., Moreno, S.N.J., Docampo, R., Croft, S.L. and Oldfield, E. (2002) In vivo activity of farnesyl pyrophosphate synthase inhibitors against Leishmania donovani and Toxoplasma gondii. Antimicrob. Agents Chemother. 46(3):929-31.
• Moreno, B., Rodrigues, C.O., Bailey, B.N., Urbina, J.A., Moreno, S.N.J., Docampo, R., and Oldfield, E. (2002) Magic-angle spinning 31P NMR spectroscopy of condensed phosphates in parasitic protozoa: visualizing the invisible. FEBS Lett. 523, 207-212.
• Jennie L. Lovett, Norma Marchesini,Silvia N.J. Moreno, and L. David Sibley. (2002) Toxoplasma gondii microneme secretion involves intracellular Ca2+ release from IP3/ryanodine sensitive stores. J. Biol. Chem. 277, 25770-25876.
• Rodrigues, C.O., Ruiz, F.A., Rohloff, P., Scott, D.A., and Moreno, S.N.J. (2002) Characterization of isolated acidocalcisomes from Toxoplasma gondii tachyzoites reveals a novel pool of hydrolysable polyphosphate. J. Biol. Chem. 277, 48650-48656.
• Marchesini, N. and Docampo, R. (2002) A plasma membrane P-type H+-ATPase regulates intracellular pH in Leishmania mexicana amazonensis. Mol. Biochem. Parasitol. 119, 225-236.
• Rodriguez, N.M., Docampo, R., Lu, H.-G., and Scott, D.A. (2002) Overexpression of the Leishmania amazonensis Ca2+-ATPase gene lmaa1 enhances virulence. Cell. Microbiol. 4, 117-126.
• Marchesini, N., Ruiz, F.A., Vieira, M., and Docampo, R. (2002) Acidocalcisomes are linked to the contractile vacuole of Dictyostelium discoideum. J. Biol. Chem. 277, 8146-8153.
• Martinez, R., Wang, Y., Benaim, G., Benchimol, M., de Souza, W., Scott, D.A., and Docampo, R. (2002) A proton pumping pyrophosphatase in the Golgi apparatus and plasma membrane vesicles of Trypanosoma cruzi. Mol. Biochem. Parasitol. 120, 205-213.
• Van der Heyden, N., and Docampo, R. (2002) Proton and sodium pumps regulate the plasma membrane potential of different stages of Trypanosoma cruzi. Mol. Biochem. Parasitol. 120, 127-139.
• Rodriguez, N., Bailey, B.N., Martin, M.B., Oldfield, E., Urbina, J.A., and Docampo, R. (2002) Radical cure of experimental cutaneous leishmaniasis by the bisphosphonate pamidronate. J. Infect. Dis. 186, 138-140.
• Elhalem, E., Bailey, B.N., Docampo, R., Ujváry, I., Szajnman, S.H., and Rodriguez, J.B. (2002) Design, synthesis and biological evaluation of aryloxyethyl thiocianate derivatives against Trypanosoma cruzi. J. Med. Chem. 45, 3984-3999.
• Lemercier, G., Dutoya, S., Luo, S., Ruiz, F.A., Rodrigues, C.O., Baltz, T., Docampo, R., and Bakalara, N. (2002) A vacuolar-type H+ pyrophosphatase governs maintenance of functional acidocalcisomes and growth of the insect and bloodstream forms of Trypanosoma brucei. J. Biol. Chem. 277, 37369-37376.
• Van der Heyden, N., and Docampo, R. (2002) Significant differences between procyclic and bloodstream forms of Trypanosoma brucei in the maintenance of their   plasma membrane potential. J. Eukaryotic Microbiol. 49, 407-413.
• Luo, S., Scott, D.A., and Docampo, R. (2002) Trypanosoma cruzi H+-ATPase 1 (TcHA1) and 2 (TcHA2) complement yeast mutants defective in H+ pumps and encode plasma membrane P-type H+-ATPases with different enzymatic properties in Trypanosoma cruzi. J. Biol. Chem. 277, 44497-44506.
• Rodrigues, C.O., Ruiz, F.A., Vieira, M., Hill, J.E., and Docampo, R. (2002) An acidocalcisomal exopolyphosphatase from Leishmania major with higher affinity for short-term polyphosphate. J. Biol. Chem. 277, 50899-50906.
• Docampo, R. (2002) Fifth Annual Conference on New and Re-Emerging Infectious Diseases. Emerging Infect. Dis. 8, 1008-1010.
• Docampo, R. (2002) New and Re-Emerging Infectious Diseases. Trends in Parasitol. 18, 334-336.
• Docampo, R., and Moreno, S.N.J. (2002) Signaling in Trypanosoma cruzi. In "World Class Parasites", vol. IV. Edited by K. M. Kyle and M. Miles., Series Ed.: J.R. Seed and S. Black, Kluwer Academic Publishers, pp. 37-44.

2001

• Shuhong L., Vieira, M. A., Zhong, L, Graves, J., and Moreno S.N.J. (2001) Cloning, functional expression and co-localization of the vacuolar Ca2+-ATPase with a vacuolar H+-pyrophosphatase to acidocalcisomes of Toxoplasma gondii. EMBO J. 20, 55-64.
• Martin, M.B., Grimley, J.S., Lewis, J.C., Heath, H.T. III, Bailey, B.N., Kendrick, H., Yardley, V., Caldera, A., Lira, R., Urbina, J.A., Moreno, S.N.J., Docampo, R., Croft, S.L., and Oldfield, E. (2001). Bisphosphonates Inhibit the Growth of Trypanosoma brucei, Trypanosoma cruzi, Leishmania donovani, Toxoplasma gondii, and Plasmodium falciparum: A Potential Route to Chemotherapy J. Med. Chem. 44, 909-916.
• Docampo, R., and Moreno, S.N.J. (2001) The acidocalcisome. Mol. Biochem, Parasitol. 33, 151-159.
• Moreno, B., Bailey, B.N., Luo, S. Martin, M.B., Kuhlenschmidt, M., Moreno, S.N.J., Docampo, R., and Oldfield, E. (2001) 31P NMR of apicomplexans and the effects of risedronate on Cryptosporidium parvum growth. Biochem. Biophys. Res. Commun. 284, 632-637
• Szajnman, S.H., Bailey B. N., Docampo, R. and Rodriguez. J. B. (2001) Bisphosphonates derived from fatty acids are potent growth inhibitors of Trypanosoma cruzi. Bioorg. Med. Chem. Lett. 11, 789-792.
• Ruiz, F.A., Rodrigues, C.O., and Docampo, R. (2001) Rapid changes in polyphosphate content within acidocalcisomes in response to cell growth, differentiation, and environmental stress in Trypanosoma cruzi. J. Biol. Chem. 276, 26114-26121.
• Rodrigues, C.O., Catisti, R., Uyemura, S.A., Vercesi, A.E., Lira, R., Rodriguez, C., Urbina, J.A., and Docampo, R. (2001) The sterol composition of Trypanosoma cruzi changes after growth in different culture media and results in different sensitivity to digitonin-permeabilization. J. Eukar. Microbiol. 48, 588-594.
• Furuya, T., Okura, M., Ruiz, F.A., Scott, D.A. and Docampo, R. (2001) TcSCA complements yeast mutants defective in Ca2+ pumps and encodes a Ca2+-ATPase that localizes to the endoplasmic reticulum of Trypanosoma cruzi. J. Biol. Chem. 276, 32447-32445.
• Montalvetti, A., Bailey, B.N., Martin, M.B, Severin, G.W., Oldfield, E., and Docampo, R. (2001) Bisphosphonates are potent inhibitors of Trypanosoma cruzi farnesyl pyrophosphate synthase. J. Biol. Chem. 276, 33930-33937.
• Ruiz, F.A., Marchesini, N., Seufferheld, M., Govindjee, and Docampo, R. (2001) The polyphosphate bodies of Chlamydomonas reinhardtii possess a proton pumping pyrophosphatase and are similar to acidocalcisomes. J. Biol. Chem. 276, 46196-46203.
• Docampo, R. and Moreno, S.N.J. (2001) The acidocalcisomal H+-translocating pyrophosphatase of trypanosomatids and apicomplexan parasites. In "New Trends in Inorganic Pyrophosphatase Research", pp. 123-126. Edited by A. Serrano. Sevilla, Universidad de Sevilla, Spain.
• Docampo, R. (2001) Recent developments in the chemotherapy of Chagas’ disease. Current Pharmaceutical Design 7, 1157-1164.
• Docampo, R., and Moreno, S.N.J. (2001) Bisphosphonates as potential antiparasitic agents against trypanosomatids and apicomplexan parasites. Curr. Drug Targets-Infectious Disorders, 7, 125-133.
• Docampo, R. (2001) Atlas of Medical Helminthology and Protozoology. Trends Parasitol. 17, 553.
• Docampo, R. (2001) Third annual conference on new and re-emerging infectious diseases: in honor of Norman Dion Levine. Acta Trop. 78, 87-88.

2000

• Vieira, M.C.F. and Moreno, S.N.J. (2000) Mobilization of intracellular calcium upon attachment of Toxoplasma tachyzoites to human fibroblasts is required for invasion. Mol. Biohem. Parasitol. 106, 157-162.
• Furuya, T., Kashuba, C., Docampo, R., and Moreno, S.N.J. (2000) A novel phosphatidylinositol-phospholipase C of Trypanosoma cruzi that is lipid modified and activated during trypomastigote to amastigote differentiation. J. Biol. Chem. 275, 6428-6438.
• Marchesini, N., Luo, S., Rodrigues, C.O., Moreno, S.N.J., and Docampo, R. (2000) Acidocalcisomes and a vacuolar H+-pyrophosphatase in malaria parasites. Biochem. J. 347, 243-253.
• Uyemura, S.A., Luo, S., Moreno, S.N.J., and Docampo, R. (2000) Oxidative phosphorylation, Ca2+ transport, and fatty acid-induced uncoupling in malaria parasites mitochondria. J. Biol. Chem. 275, 9709-9715.
• Rodrigues, C. O., Scott, D. A., Bailey, B., de Souza, W., Benchimol, M., Moreno, B., Urbina, J. A., Oldfield, E., and. Moreno S.N.J. (2000) Vacuolar proton pyrophosphatase activity and pyrophosphate in Toxoplasma gondii as possible chemotherapeutic targets. Biochem. J. 349, 737-745.
• Rodriguez, J.B., Docampo, R., and Gros, E.G. (2000) Sulfur-containing derivatives structurally related to Fenoxycarb are potent growth inhibitors against the intracellular form of Trypanosoma cruzi. Int. J. Antimicrob. Agents 13, 215-218.
• VanderHeyden, N., and Docampo, R. (2000) Intracellular pH in mammalian stages of Trypanosoma cruzi is K+-dependent and regulated by H+-ATPases. Mol. Biochem. Parasitol. 105, 237-251.
• Catisti, R., Uyemura, S.A., Docampo, R., and Vercesi, A.E. (2000) Calcium mobilization by arachidonic acid in trypanosomatids. Mol. Biochem. Parasitol., 105, 261-271.
• Vanderheyden, N., Wong, J., and Docampo, R. (2000) A pyruvate-proton symport and an H+-ATPase regulate intracellular pH of Trypanosoma brucei bloodstream forms. Biochem. J. 346, 53-62.
• Miranda, K., Benchimol, M., Docampo, R., and de Souza, W. (2000) The fine structure of acidocalcisomes in Trypanosoma cruzi. Parasitol. Res. 86, 373-384.
• VanderHeyden, N., McLaughlin, G.L., and Docampo, R. (2000) Regulation of the plasma membrane potential in Pneumocystis carinii. FEMS Microbiol. Lett., 183, 327-330.
• Szajnman, S.H., Yan, W., Bailey, B.N., Docampo, R., Elhalem, E., Rodriguez, J.B., and Gros, E.G. (2000) Design and synthesis of aryloxyethyl thiocyanate derivatives as potent inhibitors of Trypanosoma cruzi proliferation. J. Med. Chem. 43, 1826-1840.
• Vercesi, A.E., Rodrigues, C.O., Catisti, R., and Docampo, R. (2000) Presence of a Na+/H+ exchanger in acidocalcisomes of Leishmania donovani and their alkalization by anti-leishmanial agents. FEBS Lett. 473, 203-206.
• Scott, D.A., and Docampo, R. (2000) Characterization of isolated acidocalcisomes of Trypanosoma cruzi. J. Biol. Chem. 275, 24215-24221.
• Moreno, B., Urbina, J.A., Oldfield, E., Bailey, B.N., Rodrigues, C.O., and Docampo, R. (2000) 31P NMR spectroscopy of Trypanosoma brucei, Trypanosoma cruzi and Leishmania major: Evidence for high levels of condensed inorganic phosphates. J. Biol. Chem. 275, 28356-28362.
• Hill, J., Scott, D.A., Luo, S., and Docampo, R. (2000) Cloning and functional expression of a gene encoding a vacuolar-type proton-translocating pyrophosphatase from Trypanosoma cruzi. Biochem. J. 351, 281-288.
• Docampo, R. (2000) Infectious diseases: in dedication to Norman D. Levine. Parasitol. Today 16, 316-317.

1999

• Carruthers, V.B., Moreno, S.N.J., and Sibley, D. (1999) Ethanol  and acetaldehyde elevate intracellular calcium and stimulate microneme discharge in Toxoplama gondii. Biochem. J. 342, 379-386.
• Urbina, J.A., Vierkotter, S., Moreno, B., Oldfield, E., Moreno, S.N.J., Bailey, B.N., Scott, D.A., and Docampo R. (1999) Inorganic pyrophosphate is the most abundant high energy phosphate compound in trypanosomatid and apicomplexan parasites. J. Biol. Chem. 274, 33609-33615.
• Rodrigues, C.O., Scott, D.A., and Docampo, R. (1999) Presence of a vacuolar H+-pyrophosphatase in promastigotes of Leishmania donovani and its localization to a different compartment from the vacuolar H+-ATPase. Biochem. J. 340, 759-766.
• Turrens, J.F., Newton, C.L., Zhong, L., Hernandez, F.R., Whitfield, J., and Docampo, R. (1999) Mercaptopyridine-N-oxide, a NADH-fumarate reductase inhibitor, blocks Trypanosoma cruzi growth in culture and in infected myoblasts. FEMS Microbiol. Lett. 175, 217-222.
• Rodrigues, C.O., Scott, D.A., and Docampo, R. (1999) Characterization of a vacuolar pyrophosphatase in Trypanosoma brucei and its localization to acidocalcisomes. Mol. Cell. Biol. 19, 7712-7723.
• Luo, S., Marchesini, N., Moreno, S.N.J., and Docampo, R. (1999) A plant-like vacuolar H+-pyrophosphatase in Plasmodium falciparum. FEBS Lett. 460, 217-220.
• Docampo, R., and Moreno, S.N.J. (1999) Acidocalcisomes, a novel calcium storage compartment in trypanosomatids and apicomplexan parasites. Parasitol. Today 15 (11): 443-448.

1998

• Benchimol, M., de Souza, W., VanderHeyden, N., Zhong, L., Lu, H.G., Moreno S.N.J., and Docampo, R. (1998). Functional expression of a vacuolar-type H+-ATPase in the plasma membrane and intracellular vacuoles of Trypanosoma cruzi. Biochem J. 332, 695-702.
• Lu, H.-G., Zhong, L., de Souza, W., Benchimol, M., Moreno, S.N.J., and Docampo, R. (1998) Ca2+ content and expression of an acidocalcisomal calcium pump are elevated in intracellular forms of Trypanosoma cruzi. Mol. Cell. Biol. 18(4), 2309-2323.
• Zhong, L., Lu, H.-G., Moreno, S.N.J., and Docampo, R. (1998) Tyrosine phosphate hydrolysis of host proteins by Trypanosoma cruzi is linked to cell invasion. FEMS Microbiol. Lett. 161, 15-20.
• Furuya, T., Zhong, L., Meyer-Fernandes, J.R., Lu, H.-G., Moreno, S.N.J., and Docampo, R. (1998) Ecto-protein tyrosine phosphatase activity in Trypanosoma cruzi infective stages. Mol. Biochem. Parasitol. 92, 339-347.
• Scott, D.A., de Souza, W., Benchimol, M., Zhong, L., Lu, H.-G., Moreno, S.N.J., and Docampo, R. (1998) Presence of a plant-like proton-pumping pyrophosphatase in acidocalcisome of Trypanosoma cruzi. J. Biol. Chem. 273, 22151-22158.
• Vercesi, A.E., Rodrigues, C.O., Uyemura, S.A., Zhong, L., and Moreno, S.N.J. (1998) Respiration and oxidative phosphorylation in the apicomplexan parasite Toxoplasma gondii. J. Biol. Chem. 273, 31040-31047.
• Yan, W. and Moreno, S.N.J. (1998) New Method to assess invasion and intracellular replication of Trypanosoma cruzi based on differential uracil incorporation. J. Immunol Methods. 220, 123-128.
• Scott, D.A., and Docampo, R. (1998) Two types of H+-ATPase are involved in the acidification of internal compartments in Trypanosoma cruzi. Biochem. J. 331, 583-586.
• Cinque, G.M., Szajnman, S.H., Zhong, L., Docampo, R., Schvartzapel, A.J., Rodriguez, J.B., and Gros, E.G. (1998) Structure-acitivity relationship of new growth inhibitors of Trypanosoma cruzi. J. Med. Chem.  41, 1540-1554.
• Scott, D.A., Docampo, R., and Benchimol, M. (1998) Analysis of the uptake of the fluorescent marker 2’,7’-bis-(2-carboxyethyl-5(and-6)-carboxyfluorescein (BCECF) by gydrogenosomes in Trichomonas vaginalis. Eur. J. Cell Biol. 76, 139-145.
• Rodriguez, J.B., Zhong, L., Docampo, R., and Gross, E.G. (1998) Growth inhibitory effect of juvenile hormone analogues on epimastigotes of Trypanosoma cruzi. BioMed Chem. Lett. 8, 3257-3260.

1997

• Moreno, S.N.J., Zhong, L., Lu, H. G., de Souza, W., and Benchimol, M. (1997) A vacuolar type H+-ATPase regulates cytoplasmic pH in Toxoplasma gondii tachyzoites. Biochem J.  330, 853-860.
• Lu, H.G., Zhong, L., Chang. K.P., and Docampo, R. (1997) Intracellular Ca2+ pool content and signaling and expression of a calcium pump are linked to virulence in Leishmania mexicana amazonensis. J. Biol. Chem. 272, 9646-9473.
• Urbina, J.A., Visbal, G., Contreras, L.M., McLaughlin, G. and Docampo, R. (1997) Inhibitors of D24(25) sterol methyl transferease block sterol synthesis and cell proliferation in Pneumocystis carinii. Antimicrob. Agents Chemother. 41, 1428-1432.
• Schvartzapel, A.J., Zhong, L., Docampo,.R., Rodriguez, J.B., and Gros, E.G. (1997) Design, synthesis, and biological evaluation of new growth inhibitors of Trypanosoma cruzi (epimastigotes). J. Med. Chem. 40, 2314-2322.
• Scott, D.A., Docampo, R., Dvorak, J.A., Shi, S., and Leapman, R.D. (1997) In situ compositional analysis of acidocalcisomes in Trypanosoma cruzi. J. Biol. Chem. 272, 28020-28029.
• Vercesi, A.E., Grijalba, M., and Docampo, R. (1997) Inhibition of Ca2+ release from Trypanosoma brucei acidocalcisomes by 3,5-dibutyl-4-hydroxytoluene (BHT): role of the Na+/H+ exchanger. Biochem. J. 328, 479-482.
• Docampo, R., and Schmuñis, G.A. (1997) Sterol biosynthesis inhibitors as potential chemotherapeutic agents against Chagas' disease. Parasitol. Today 13, 129-130.

1996

• Moreno, S.N.J. (1996) Pentamidine is an uncoupler of oxidative phosphorylation in rat liver mitochondria. Arch. Biochem. Biophys. 326 (1), 15-20.
• Moreno, S.N.J. and Zhong L. (1996) Acidocalcisomes in Toxoplasma gondii tachyzoites. Biochem J.  313, 655-659.
• Vercesi, A.E., and Docampo, R. (1996) Sodium-proton exchange stimulates Ca2+ release from acidocalcisomes of Trypanosoma brucei. Biochem. J. 315, 265-270.
• Docampo, R., VanderHeyden, N., Shaw, M.M., Durant, P.J., Bartlett, M.S., Smith, J.W., and McLaughlin, G.L. (1996) An H+-ATPase regulates cytoplasmic pH in Pneumocystis carinii trophozoites. Biochem. J. 316, 681-684.
• Suju, M., Davila, M., Poleo, G., Docampo, R., and Benaim, G. (1996) Phosphatidylethanol stimulates the plasma-membrane calcium pump from human erythrocytes. Biochem. J. 317, 933-938.
• VanderHeyden, N., Benaim, G., and Docampo, R. (1996) The role of a H+-ATPase in the regulation of cytoplasmic pH in Trypanosoma cruzi epimastigotes. Biochem. J. 318, 103-109.
• Turrens, J.F., Watts, B., Zhong, L., and Docampo, R. (1996) Inhibition of Trypanosoma cruzi and T. brucei NADH fumarate reductase by benznidazole and anthelmintic imidazole derivatives. Mol. Biochem. Parasitol. 82, 125-129.
• Rodriguez, J.B., Zhong, L., Docampo, R., and Gros, E.G. (1996) Biological evaluation of two potent inhibitors of Trypanosoma cruzi epimastigotes against the intracellular form of the parasite. Bioorganic & Medicinal Chemistry Letters 6: 2783-2786.
• Docampo, R. (1996) Calcium metabolism and cell function. Parasitol. Today 12, 61-65.
• Docampo R. and Moreno, S.N.J. (1996) The role of calcium in the process of cell invasion by intracellular parasites. Parasitol.Today 12 (2) 61-66.

1995

• Benaim, G., Moreno, S.N.J., Hutchinson,G. Cervino,V., Hermoso, T., Romero, P.J. Ruiz, F., de Souza, W. and Docampo, R. (1995) Characterization of the plasma membrane calcium pump from Trypanosoma cruzi. Biochem J. 306,299-303.
• Hoffmann, M.E., Jang, J., Moreno S.N.J., and Docampo, R. (1995) Inhibition of protein synthesis and amino acid transport by crystal violet in Trypanosoma cruzi. J. Eukariot. Microbiol 42 (3), 293-297.
• Docampo,R., Scott, D.A., Vercesi, A.E. and Moreno, S.N.J. (1995) Intracellular calcium storage in acidocalcisomes of Trypanosoma cruzi. Biochem J. 310 (3), 1005-1012.
• Scott, D.A., Moreno, S.N.J., and Docampo R. (1995) Calcium storage in Trypanosoma brucei: The influence of cytoplasmic pH and importance of vacuolar acidity. Biochem J.  310 (3), 789-794.
• Docampo, R. (1995) Antioxidant Mechanisms. In "Biochemistry and Molecular Biology of Parasites ". pp. 147-160. Edited by J.J. Marr and M. Müller. New York, Academic Press, New York.

1994

• Moreno, S. N. J., Carnieri, E.G.S., and Docampo, R (1994) Inhibition of Trypanosoma cruzi trypanothione reductase by crystal violet. Mol. Biochem. Parasitol. 67: 313-320.
• Moreno, S.N.J., Silva, J., Vercesi, A.E., and Docampo, R. (1994) Cytosolic free calcium elevation in Trypanosoma cruzi  is required for cell invasion. J Exp. Med. 180, 1535-1540.
• Vercesi, A.E., Moreno, S.N.J., and Docampo, R. (1994) Ca2+/H+ exchange in acidic vacuoles of Trypanosoma brucei. Biochem. J.  304, 227-233.

1993

• Docampo, R., Gadelha, F.R., Moreno, S.N.J., Benaim, G., Hoffmann, M.E., and Vercesi, A.E. (1993) Disruption of Ca2+ homoestasis in Trypanosoma cruzi by crystal violet. J. Euk. Microbiol. 40, 311-316.
• Vercesi, A.E., Moreno, S.N.J., Bernardes, C.F., Meinicke, A.R., Fernandes, E.C., and Docampo, R. (1993) Thapsigargin causes Ca2+ release and collapse of the membrane potential of Trypanosoma brucei mitochondria in situ and of isolated rat liver mitochondria. J. Biol. Chem. 268, 8564-8568.
• Docampo, R., Moreno, S.N.J., and Vercesi, A.E. (1993) Effect of thapsigargin on calcium homeostasis in Trypanosoma cruzi trypomastigotes and epimastigotes. Mol. Biochem. Parasitol.  59, 305-315
• Carnieri, E.G.S., Moreno, S.N.J., and Docampo, R. (1993) Trypanothione-dependent peroxide metabolism in Trypanosoma cruzi different stages. Mol. Biochem. Parasitol. 61, 79-86.
• Benaim, G., Lopez-Estraño, C., Docampo, R., and Moreno, S.N.J. (1993) A calmodulin-stimulated Ca2+-pump in plasma membrane vesicles from Trypanosoma brucei. Selective inhibition by pentamidine. Biochem J. 296, 759-763.
• Vercesi, A.E., Hoffmann, M.E., Bernardes, C.F., and Docampo, R. (1993) ATP and Ca2+ homeostasis in Trypanosoma cruzi. Brazilian J. Med. Biol. Res. 26, 355-363.
• Docampo, R. (1993) Calcium homeostasis in Trypanosoma cruzi. Biol. Res. 26, 189-196.

1992

• Moreno, S.N.J., Docampo, R. and Vercesi, A.E. (1992) Calcium homeostasis in procyclic and bloodstream forms of Trypanosoma brucei. Lack of inositol 1,4,5-trisphosphate-sensitive Ca2+ release. J. Biol. Chem. 267, 6020-6026.
• Moreno, S.N.J., Vercesi, A.E., Pignataro, O.P., and Docampo, R. (1992) Calcium homeostasis in Trypanosoma cruzi amastigotes. Presence of inositol phosphates and absence of an inositol 1,4,5-trisphosphate-sensitive Ca2+ pool. Mol. Biochem. Parasitol. 52, 251-262.
• Vercesi, A.E., Docampo, R., and Moreno, S.N.J. (1992) Energization-dependent Ca2+ accumulation in Trypanosoma brucei bloodstream and procyclic trypomastigotes mitochondria. Mol. Biochem. Parasitol. 56, 251-258.
• Vercesi, A.E., and Docampo, R. (1992) Ca2+ transport by digitonin-permeabilized Leishmania donovani. Effect of Ca2+, pentamidine and WR-6026 on mitochondrial membrane potential in situ. Biochem. J. 284, 463-467.
• Gadelha, F.R., Hanna, P.M., Mason, R.P., and Docampo, R. (1992) Evidence for free radical formation during horseradish peroxidase-catalyzed N-demethylation of crystal violet. Chemico-Biol. Interact. 85, 35-48.
• Docampo, R. (1992) Participation of ferredoxin in the reduction of nitroimidazoles by Tritrichomonas foetus hydrogenosomes. An. Asoc. Quim. Argent. 80, 27-34.

1991

• Moreno, S.N.J., Ip, H.S., and Cross, G.A.M. (1991) An mRNA-dependent in vitro translation system from Trypanosoma brucei. Mol. Biochem. Parasitol. 46, 265-274.
• Docampo, R., and Pignataro, O.P. (1991) The inositol phosphate/diacylglycerol signalling pathway in Trypanosoma cruzi. Biochem. J. 275, 407-411.
• Vercesi, A.E., Hoffmann, M.E., Bernardes, C.F., and Docampo, R. (1991) Regulation of intracellular calcium homeostasis in Trypanosoma cruzi. Effects of calmidazolium and trifluoperazine. Cell Calcium 12, 361-369.
• Vercesi, A.E., Bernardes, C.F., Hoffmann, M.E., Gadelha, F.R., and Docampo, R. (1991) Digitonin permeabilization does not affect mitochondrial function and allows the determination of the mitochondrial membrane potential of Trypanosoma cruzi in situ. J. Biol. Chem. 266, 14431-14434.
• Benaim, G., Losada, S., Gadelha, F.R., and Docampo, R. (1991) A calmodulin-activated (Ca2+-Mg2+)-ATPase is involved in Ca2+ transport by plasma membrane vesicles from Trypanosoma cruzi. Biochem. J. 280, 715-720.
• Docampo, R., and Moreno, S.N.J. (1991) The metabolism and mode of action of gentian violet.  Drug. Met. Rev. 22, 1-27, 161-178.
• Docampo, R. Gadelha, F. and Moreno, S.N.J. (1991) Metabolism and Mode of Anti-Trypanosoma cruzi action of gentian violet.. In Molecular and Immunological Aspects of Parasitism pg. 95-104. Editor C.C. Wang. Washington D.C., American Association for the Advancement of Science.

1990 and before

• Docampo, R., and Moreno, S.N.J. (1990) The metabolism and mode of action of gentian violet.. Drug. Met. Rev. 22, 1-27, 161-178.
• Docampo, R. (1990) Male Contraception and Chemotherapy for trypanosomiasis and Leshmaniasis: An Analysis of Biochemical Similarities and Considerations for Future Research. In Cellular and Molecular Events in Spermiogenesis pp. 285-308. Edited by D. Hamilton, and G.M.H. Waites. London: Cambridge University Press.
• Docampo, R. (1990) Sensitivity of parasites to free radical damage by antiparasitic drugs. Chem.-Biol. Interact. 73, 1-27.
• Vercesi, A.E., Macedo, D.V., Lima, S.A., Gadelha, F.R., and Docampo, R. (1990) Ca2+ transport in digitonin-permeabilized trypanosomatids. Mol. Biochem. Parasitol. 42, 119-124.
• Moreno, S.N.J. (1989) The reductive metabolism of nifurtimox and benznidazole in Crithidia fasciculata is similar to that in Trypanosoma cruzi.. Comp. Biochem. Biophys. 91C, 321-325.
• Gadelha, F.R., Moreno, S.N.J., de Souza, W., Cruz, F.S, and Docampo, R. (1989) The mitochondrion of Trypanosoma cruzi is a target of crystal violet toxicity. Mol. Biochem. Parasitol. 34, 117-126.
• Stolze, K., Moreno, S.N.J., and Mason, R.P. (1989) Free radical intermediates formed during the oxidation of cyanide by horseradish peroxidase/H2O2 as detected with nitroso spin traps. J. Inorg. Biochem. 37, 45-53.
• Moreno, S.N.J. and Docampo, R. (1989) Reduction of 5-Nitroimidazoles, Nitrofurazone, and 2,4-Dinitrophenol to their Free Radical Metabolites by Tritrichomonas foetus hydrogenosomes.. In Oxygen Radicals in Biology and Medicine, pp. 759-764. Edited by M.G. Simic, K.A. Taylor, J.F. Ward, and C. von Sonntag. New York, Plenum Publishing Corporation.
• Docampo, R., and Vercesi, A.E. (1989) Ca2+ transport by coupled Trypanosoma cruzi mitochondria in situ. J. Biol. Chem. 264, 108-111.
• Docampo, R., and Vercesi, A.E. (1989) Characteristics of Ca2+ transport by Trypanosoma cruzi mitochondria in situ. Arch. Biochem. Biophys. 272, 122-129.
• Docampo, R., Moreno, S.N.J., and Cruz, F.S. (1988) Enhancement of the cytotoxicity of crystal violet against Trypanosoma cruzi in the blood by ascorbate.. Mol. Biochem. Parasitol. 27, 241-248.
• Docampo, R., Moreno, S.N.J., and Mason, R.P. (1988) Generation of superoxide anion and hydrogen peroxide during redox cycling of 5(-4-nitrophenyl)penta-2,4-dienal (NPPD) by mammalian microsomes and enzymes. Chem.-Biol. Interact. 65, 123-131.
• Moreno, S.N.J., Stolze, K., Janzen, E.G., and Mason, R.P. (1988) Oxidation of cyanide to the cyanyl radical by peroxidase/H2O2 systems as determined by spin trapping. Arch. Biochem. Biophys. 265, 267-271.
• Moreno, S.N.J., Gadelha, F.R., and Docampo, R. (1988) Crystal violet as an uncoupler of oxidative phosphorylation in rat liver mitochondria. J. Biol. Chem. 263, 12493-12499.
• Docampo, R., Moreno, S.N.J., Gadelha, F.R., de Souza, W., and Cruz, F.S. (1988) Prevention of Chagas'disease resulting from blood transfusion by treatment of blood: toxicity and mode of action of gentian violet. Biomed. Environm. Sci. 1, 406-413.
• Docampo, R., Moreno, S.N.J. and Mason, R.P. (1987) Free radical intermediates in the reaction of pyruvate:ferredoxin oxidoreductase in Tritrichomonas foetus hydrogenosomes. J. Biol. Chem. 262, 12417-12420.
• Morehouse, K.M., Moreno, S.N.J., and Mason, R.P. (1987) The one-electron reduction of uroporphyrin I by rat hepatic microsomes. Arch. Biochem. Biophys. 257, 276-284.
• Albonico, S.M., Assem, M.E., Benages, A.A., Montiel, A.A., Pizzorno, M.T., Docampo, R., and Stoppani, A.O.M. (1987) Synthetic trypanocides: growth-inhibiting properties of new 1,2,3,4-tetrahydrocarbazoles on Trypanosoma cruzi. Rev. Asoc. Arg. Microbiol. 19, 121-124.
• Docampo, R. and Moreno, S.N.J. (1986) Free radical metabolism of antiparasitic agents. Fed. Proceed. 45, 2471-2476.
• Moreno, S.N.J., Schreiber, J., and Mason, R.P. (1986) Nitrobenzyl radical metabolites from microsomal reduction of nitrobenzyl chlorides. J. Biol. Chem. 21, 7811-7815.
• Marr, J.J., and Docampo, R. (1986) Chemotherapy of Chagas' disease. A perspective of current therapy and considerations for future research. Rev. Infect. Dis. 8, 884-903.
• Reszka, K., Cruz, F.S., and Docampo, R. (1986) Photosensitization by the trypanocidal agent gentian violet. Type I versus Type II reactions. Chem.-Biol. Interact. 58, 161-172.
• Moreno, S.N.J. and Docampo, R. (1985) The mechanism of toxicity of nitro compounds used in the chemotherapy of trichomoniasis. Environm. Hlth Perspect. 64, 199-208.
  Moreno, S.N.J., Mason, R.P., and Docampo, R. (1985) Reduction of the metallochromic indicators arsenazo III and antipyrylazo III to their free radical metabolites by cytoplasmic enzymes. FEBS Lett. 180, 229-233.
• Moreno, S.N.J. and Docampo, R. (1985) Reduction of the metallochromic indicators murexide and tetramethylmurexide to their free radical metabolites by cytoplasmic enzymes and reducing agents. Chem.-Biol. Interact. 57, 17-25.
• Docampo, R. and Moreno, S.N.J. (1985) Biochemical Toxicology of Antiparasitic Drugs Used in the Chemotherapy and Chemoprophylaxis of American Trypanosomiasis (Chagas' Disease). In Reviews in Biochemical Toxicology, Vol. VII, pp. 159-204. Edited by E. Hodgson, J.R. Bend, and R.M. Philpot. New York, Elsevier Biomedical.
• Cardoni, R.L., de Titto, E.H., and Docampo, R. (1985) On the mechanism of killing of Trypanosoma cruzi by human polymorphonuclear leukocytes. Experientia 41, 89-91.
• Docampo, R. and Moreno, S.N.J. (1984) Free radical metabolites in the mode of action of chemotherapeutic agents and phagocytic cells on Trypanosoma cruzi.. Rev. Infect. Dis. 6, 223-238.
• Moreno, S.N.J., Mason, R.P., and Docampo, R. (1984) Reduction of nifurtimox and nitrofurantoin by intact rat liver mitochondria. Evidence of an outer membrane-located nitroreductase. J. Biol. Chem. 259, 6298-6305.
• Moreno, S.N.J., Mason, R.P., and Docampo, R. (1984) Distinct reduction of nitrofurans and metronidazole to free radical metabolites by Tritrichomonas foetus hydrogenosomal and cytosolic enzymes. J. Biol. Chem.. 259, 8252-8259.
• Cruz, F.S., Lopes, L.A.V., De Souza, W., Moreno, S.N.J., Mason, R.P., and. Docampo, R. (1984) The photodynamic action of rose bengal on Trypanosoma cruzi. Acta Trop. 41, 99-108.
• Moreno, S.N.J., Mason, R.P., and Docampo, R. (1984) Ca2+ and Mg2+-enhanced reduction of arsenazo III to its anion free radical metabolite and generation of superoxide anion by an outer mitochondrial membrane azoreductase. J. Biol. Chem. 259, 14609-14616.
• Docampo, R. and Moreno, S.N.J. (1984) Free Radical Intermediates in the Antiparasitic Action of Drugs and Phagocytic Cells. In Free Radicals in Biology, Vol. 6, pp. 243-288. Edited by W.A. Pryor. New York, Academic Press.
• Docampo, R., and Moreno, S.N.J.  (1984) Free Radical Intermediates in the Trypanocidal Action of Drugs and Phagocytic Cells.. In Oxygen Radicals in Chemistry and Biology, pp. 749-752. Edited by W. Bors, M. Saran, and D. Tait. Berlin, Walter de Gruyter.
• Docampo, R., Dubin, M., Martino E.E., Moreno, S.N.J. and Stoppani, A.O.M. (1983) Effect of nifurtimox on glutathione content in liver and bile in the rat. Medicina (Buenos Aires) 43, 33-40.
  Moreno, S.N.J., Docampo, R., and Stoppani, A.O.M. (1983) About undesirable effects of nifurtimox and benznidazole. Medicina (Buenos Aires) 43, 291-296.
• Docampo, R., Casellas, A.M., Madeira, E.D., Cardoni, R.L., Moreno, S.N.J., and Mason, R.P. (1983) Oxygen-derived radicals from Trypanosoma cruzi-stimulated human neutrophils. FEBS Lett. 155, 25-30.
• Moreno, S.N.J., Mason, R.P., Muniz, R.P.A., Cruz, F.S., and Docampo, R. (1983) Generation of free radicals from metronidazole and other nitroimidazoles by Tritrichomonas foetus. J. Biol. Chem. 258, 4051-4054.
• Docampo, R., Moreno, S.N.J., Muniz, R.P.A., Cruz, F.S., and Mason, R.P. (1983) Light-enhanced free radical formation and trypanocidal action of gentian violet (crystal violet). Science  220, 1292-1295.
• Docampo, R., Moreno, S.N.J. and Mason, R.P. (1983) Generation of free radical metabolites and superoxide anion by the calcium indicators arsenazo III, antipyrylazo III, and murexide in rat liver microsomes. J. Biol. Chem. 258, 14920-14925.
• Moreno, S.N.J., Docampo, R., Mason, R.P., Leon, W. and Stoppani, A.O.M. (1982) Different behaviors of benznidazole as free radical generator with mammalian and Trypanosoma cruzi  microsomal preparations. Arch. Biochem. Biophys. 218, 585-591.
• Dubin, M., Moreno, S.N.J., Martino, E.E., Docampo, R., and Stoppani, A.O.M. (1982) Increased biliary secretion and loss of hepatic glutathione in rat liver after nifurtimox treatment. Biochem. Pharmacol. 32, 483-487.
• Docampo, R. , Cardoni,R.L.,  Casellas, A.M. and  De Souza, W. (1982) Antibody-dependent Cytolysis of Trypanosoma cruzi by Polymorphonuclear Leukocytes:       Dependence on the Respiratory burst.  In Nuclear Techniques in the Study of Parasitic Infections, pp. 61-71. Vienna; International Atomic Energy Agency.
• Cannata, J.J.B., Valle, E., Docampo, R., and Cazzulo, J.J. (1982) Subcellular localization of phosphoenolpyruvate carboxykinase in the trypanosomatids Trypanosoma cruzi and Crithidia fasciculata. Mol. Biochem. Parasitol. 6, 151-160.
• Salzman, T.A., Stella, A.M., Wider de Xifra, E., del Batlle, C.A.M.C., Docampo, R., and Stoppani, A.O.M. (1982) Porphyrin biosynthesis in parasitic hemoflagellates: functional and defective enzymes in Trypanosoma cruzi. Comp. Biochem. Physiol. B72, 663-667.
• Cardoni, R.L., Docampo, R., and Casellas, A.M. (1982) Metabolic requirements for the damage of Trypanosoma cruzi epimastigotes by human polymorphonuclear leukocytes. J. Parasitol. 68, 547-552.
• Docampo, R., Moreno, S.N.J., Stoppani, A.O.M., Cruz, F.S., Leon, W., Villalta, F., and Muniz, R.P.A. (1981) Mechanism of nifurtimox toxicity in different stages of Trypanosoma cruzi. Biochem. Pharmacol. 30, 1947-1951.
• Docampo, R., Moreno, S.N.J., Turrens, J.F., Katzin, A.M., Gonzalez-Cappa, S.M., and Stoppani, A.O.M. (1981) Biochemical and ultrastructural alterations produced by miconazole and econazole in Trypanosoma cruzi. Mol. Biochem. Parasitol. 3, 169-180.
• Docampo, R., Moreno, S.N.J., and Stoppani, A.O.M. (1981) Nitrofuran enhancement of microsomal electron transport, superoxide anion production and lipid peroxidation. Arch. Biochem. Biophys. 207, 316-322.
• Stoppani, A.O.M., Docampo, R., and Moreno, S.N.J. (1981) Biochemical basis of Chagas' disease chemotherapy. Rev. Asoc. Med. Arg. 175-180, Set-Dec.
• Docampo, R., Mason, R.P., Mottley, C., and Muniz, R.P.A. (1981) Generation of free radicals induced by nifurtimox in mammalian tissues. J. Biol. Chem. 256, 10930-10933.
• Moreno, S.N.J., Palmero, D.J., de Palmero K.E., Docampo, R., and A.O.M. Stoppani (1980) Stimulation of lipid peroxidation and ultrastructural alterations induced by nifurtimox in mammalian tissues. Medicina (Buenos Aires) 40, 563-559.
• Boiso, J.F. de, Docampo, R., and Stoppani, A.O.M. (1980) Antimycin inhibition of respiration and growth of Trypanosoma cruzi. Medicina (Buenos Aires) 39, 362-368.
• Docampo, R., and Stoppani, A.O.M. (1980) Generation of oxygen reduction derivatives induced by nifurtimox and other nitrocompounds in Trypanosoma cruzi. Medicina (Buenos Aires) 40, 10-16.
• Docampo, R. (1980) Generation of Free Radicals from Nifurtimox in Trypanosoma cruzi and in the mammalian host. In The Host Invader Interplay, pp. 677-681. Edited by H.Van den Bossche, Amsterdam: Elsevier-North Holland.
• Cannata, J.J.B., Docampo, R., Valle, E., Franke de Cazzulo, and Cazzulo, J.J. (1980) Intracellular distribution of CO2-fixing enzymes in Trypanosoma cruzi and Crithidia fasciculata. Medicina (Buenos Aires) 40, 145-153.
• Docampo, R. (1980) Generation of free radicals induced by nifurtimox in mammalian tissues. Rev. Soc. Arg. Biol. 56, 15-27.
• Boveris, A., Sies, H., Martino, E.E., Docampo, R., Turrens, J.F., and Stoppani, A.O.M. (1980) Deficient metabolic utilization of H202 in Trypanosoma cruzi. Biochem. J. 188, 643-648.
• Goncalves, A.M., Vasconcellos, M.E.L., Docampo, R., Cruz, F.S., De Souza, W., and Leon, W. (1980) Evaluation of the toxicity of 3-allyl-b-lapachone against Trypanosoma cruzi bloodstream forms. Mol. Biochem. Parasitol. 1, 167-176.
• Cazzulo, J.J., Valle, E., Docampo, R., and Cannata, J.J.B. (1980) Intracellular distribution of CO2 fixing enzymes in Trypanosoma cruzi and Crithidia fasciculata. J. Gen. Microbiol. 117, 271-274.
• Stoppani, A.O.M., Docampo, R., Boiso, J.F. de, and Frasch, A.C.C. (1980) Effect of inhibitors of electron transport and oxidative phsophorylation on Trypanosoma cruzi respiration and growth. Mol. Biochem. Parasitol. 2, 3-21.
• Docampo, R., Cruz, F.S., Leon, W., and Schmunis, G.A. (1979) Acetate oxidation by bloodstream forms of Trypanosoma cruzi. J. Protozool. 26, 301-303.
• Docampo, R., Cruz, F.S., Boveris, A., Muniz, R.P.A., and Esquivel, D.M.S. (1979) b-Lapachone enhancement of lipid peroxidation and superoxide anion and hydrogen peroxide formation by sarcoma 180 ascitis tumor cells. Biochem. Pharmacol. 28, 723-729.
• De Souza, W., Souto-Padron, T., Docampo, R., Chaves, L., and Leon, W. (1979) The presence of basic proteins associated to the kinetoplast DNA of Trypanosoma cruzi epimastigotes. Acta Trop. 36, 253-255.
• Docampo, R., and Stoppani, A.O.M. (1979) Generation of superoxide anion and hydrogen peroxide induced by nifurtimox in Trypanosoma cruzi. Arch. Biochem. Biophys. 197, 317-321.
• Boiso, J.F. de, Docampo, R., and Stoppani, A.O.M. (1979) Cytochromes in culture forms of Trypanosoma cruzi. Rev. Asoc. Arg. Microbiol. 11, 22-36.
• Docampo, R., Boiso, J.F. de, and Stoppani, A.O.M. (1978) Tricarboxylic acid cycle operation at the kinetoplast-mitochondrion  complex of Trypanosoma cruzi. Biochim. Biophys. Acta 502, 466-476.
• Cruz, F.S., Docampo, R., and De Souza, W. (1978) Effect of b-lapachone on hydrogen peroxide production in Trypanosoma cruzi.  Acta Trop. 35, 35-40.
• Docampo, R., Cruz, F.S., Boveris, A., Muniz, R.P.A., and Esquivel, D.M.S. (1978) Lipid peroxidation and the generation of free radicals, superoxide anion and hydrogen peroxide in b-lapachone-treated Trypanosoma cruzi epimastigotes. Arch. Biochem. Biophys. 186, 292-297.
• Lopes, J.N., Cruz, F.S., Docampo, R., Vasconcellos, M.E.L., Sampaio, M.C.R., Pinto, A.V., and Gilbert, B. (1978)  "In vitro" and "in vivo" evaluation of the toxicity of 1,4-naphthoquinones and 1,2-naphthoquinone derivatives against Trypanosoma cruzi. Ann. Trop. Med. Parasitol. 72, 521-531.
• Docampo, R., Cruz, F.S., Muniz, R.P.A., Esquivel, D.M.S., and Vasconcellos, M.E.L. (1978) Generation of free radicals from phenazine methosulfate in Trypanosoma cruzi epimastigotes. Acta Trop. 35, 221-228.
• Leon, L., Vasconcellos, M.E.L., Leon, W., Cruz, F.S., Docampo, R., and De Souza, W. (1978) Trypanosoma cruzi: Effect of olivacine on macromolecular synthesis, ultrastructure and respiration of epimastigotes. Exp. Parasitol. 45, 151-159.
• Boveris, A., Docampo, R., Turrens, J.F., and Stoppani, A.O.M. (1978) Effect of b-lapachone and a-lapachone on superoxide anion and hydrogen peroxide production in Trypanosoma cruzi. Biochem. J. 175, 431-439.
• Boveris, A., Stoppani, A.O.M., Docampo, R., and Cruz, F.S. (1978) Superoxide anion production and trypanocidal action of naphthoquinones on Trypanosoma cruzi. Comp. Biochem. Physiol. C61, 327-329.
• Cruz, F.S., Docampo, R., and Boveris, A. (1978) Effect of b-lapachone on peroxide production in bacteria. Antimicrob. Agents Chemother. 14, 630-633.
• Docampo, R., De Souza, W., Cruz, F.S., Roitman, I., Cover, B., and Gutteridge, W. (1978) Ultrastructural alterations and peroxide formation induced by naphthoquinones in different stages of Trypanosoma cruzi. Z. Parasitenkd. (Parasitol. Res.) 57, 189-198.
• Boiso, J.F. de, Docampo, R., and Stoppani, A.O.M. (1977) Histochemical investigation of microperoxisomes in Trypanosoma cruzi. Medicina (Buenos Aires) 37, 365-370.
• Boveris, A., Docampo, R., Turrens, J.F., and Stoppani, A.O.M. (1977) Effect of a- and b-lapachone on H202 production and growth of Trypanosoma cruzi. Rev. Asoc. Arg. Microbiol. 9, 54-61.
• Docampo, R., Lopes, J.N., Cruz, F.S., and De Souza, W. (1977) Trypanosoma cruzi: Ultrastructural and metabolic alterations of epimastigotes by b-lapachone. Exp. Parasitol. 42, 142-149.
• Docampo, R., Boiso, J.F. de, and Stoppani, A.O.M. (1976) Glyceraldehyde-3-phosphate dehydrogenase activity in soluble extracts of the epimastigote form of Trypanosoma cruzi.  Rev. Asoc. Arg. Microbiol. 8, 21-25.
• Docampo, R., Boiso, J.F. de, and Stoppani, A.O.M. (1976) Identification of microperoxisomes in Trypanosoma cruzi. Rev. Soc. Arg. Biol. 52, 44-49.
• Docampo, R., Boiso, J.F. de, and Stoppani, A.O.M. (1976) Localization of peroxidase activity in Trypanosoma cruzi microbodies.  Experientia 32, 365-370.
• Docampo, R., Boiso, J.F. de, and Stoppani, A.O.M. (1974) Metabolic alterations in diskinetoplastic Trypanosoma cruzi.  Medicina (Buenos Aires) 34, 525-531.
• Docampo, R., Boiso, J.F. de, and Stoppani, A.O.M. (1974) Scanning and transmission electron microscopy studies of Trypanosoma cruzi. Rev. Soc. Arg. Biol. 50, 93-100.
• Docampo, R., Boiso, J.F. de, and Stoppani, A.O.M. (1974) Metabolic differences in Trypanosoma cruzi cultivated in different media. Rev. Asoc. Arg. Microbiol. 6, 7-14.
• Docampo, R., Boiso, J.F. de, and Stoppani, A.O.M. (1974) New observations on the ultrastructure of Trypanosoma cruzi by scanning and transmission electron microscopy.  Rev. Asoc. Arg. Microbiol. 6, 119-126.
• Docampo, R., Boiso, J.F. de, and Stoppani, A.O.M. (1973) Trypanosoma cruzi growth in diphasic and liquid medium. Effect of ethidium bromide. Rev. Asoc. Arg. Microbiol. 5, 117-122

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